Computational Biology Platform

Sequence analysis, protein
folding, and drug discovery.
One workspace.

Talindrew connects your sequence editor, structure prediction, cloning designer, and docking pipeline in a single browser-based environment. No file exports. No context switching.

ESMFoldAutoDock VinaTemporalRDKit

01 — Sequence & Structure

From raw nucleotides to folded protein

Edit sequences with colored bases, ORF detection, and restriction site mapping. Fold with ESMFold on GPU. View as linear tracks or circular plasmid maps.

BRCA1_exon11.fasta
LinearCircular
1102030405060708090100110
ORF 1EcoRI
5'ATGGATTTATCTGCTCTTCGCGTTGAAGAAGTACAAAATGTCATTAATGCTATGCAGA
3'TACCTAAATAGACGAGAAGCGCAACTTCTTCATGTTTTACAGTAATTACGATACGTCT
DNA1,863 bpGC 41.2%3 ORFs
LinearCircular
BRCA1AmpRoripUC192,686 bp
ESMFold — 395aa
Ribbon · spectrum
pLDDT
0.88
Confidence
HIGH

02 — Molecular Cloning

Visual cloning workflow execution

Restriction, Gibson, Golden Gate, In-Fusion, Gateway, TA, TOPO, and NEBuilder — all as drag-and-drop node graphs. Click a strategy to see its workflow.

Execution Log
Waiting for execution...
BioPython Agent
Gibson assembly validated. All overlaps ≥25 bp. No off-target sites detected.

03 — Drug Discovery

Multi-stage pipeline. Sequence to ranked candidates.

FoldRx: protein folding, pocket detection (orthosteric + cryptic), AutoDock Vina docking, ADMET profiling, selectivity, and synthesis scoring.

FoldRx — Drug Discovery Pipeline
1
Sequence
2
Folding
3
Pockets
4
Docking
5
ADMET
6
FEP
7
Selectivity
8
Ranking

Approach

Why this works

01

One platform, not five.

Sequence editing, restriction analysis, cloning design, protein folding, and drug docking — in one browser tab. No FASTA exports between disconnected tools.

02

Open infrastructure.

FastAPI backend, Temporal workflow engine, MCP protocol for AI agents. Every component is API-accessible. No vendor lock-in.

03

GPU when you need it.

ESMFold runs on Colab Enterprise L4/A100 GPUs. Temporal orchestrates multi-stage pipelines with crash recovery and heartbeating. Scale down to zero when idle.

Interested in Talindrew for your team?

We're working with early research teams to refine the platform. Reach out if you'd like a walkthrough of the pipeline.

Request a Demo